The first municipality in the Aosta Valley is Pont-Saint-Martin. After passing the municipalities of Donnas, the fort of Bard, Hône, Arnad, Verrès and Montjovet, the short climb of the "Mongiovetta" begins which takes you to Saint-Vincent and then to Châtillon. Then after crossing Chambave, Champagne (Verrayes) and Nus, you arrive at the gates of Aosta, where the state road becomes two lanes in each direction in the municipalities of Quart and Saint-Christophe (commercial area).
After a possible stop in Aosta, having passed the Aosta Valley capital (Corso Ivrea, Via Roma and Via Parigi with numerous roundabouts) and after the crossroads which leads to the Great Saint Bernard state road N. 27, the road 26 continues westwards and crosses Sarre (crossroads for Cogne), Saint-Pierre, Villeneuve (crossroads for Introd and the valleys of Rhêmes and Valsavarenche), Arvier, Léverogne (crossroads for Valgrisenche), passes near Derby (fraction of La Salle), crosses La Salle and then Morgex until you reach Pré-Saint-Didier (crossroads for La Thuile and, in summer, for the Little Saint-Bernard pass). From here continue to Courmayeur.
To return you can opt for the transfer route along the A5 motorway, which crosses the entire central valley, from Courmayeur to Pont-Saint-Martin. You will find indicated all the toll booths and exits that you may need to reach the starting points of the motorbike itineraries or to return home at the end of your excursions.